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Nuclear phosphorylated Dicer processes double-stranded RNA in response to DNA damage

The endoribonuclease Dicer is a key component of the human RNA interference pathway and is known for its role in cytoplasmic microRNA production. Recent findings suggest that noncanonical Dicer generates small noncoding RNA to mediate the DNA damage response (DDR). Here, we show that human Dicer is...

詳細記述

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書誌詳細
出版年:J Cell Biol
主要な著者: Burger, Kaspar, Schlackow, Margarita, Potts, Martin, Hester, Svenja, Mohammed, Shabaz, Gullerova, Monika
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551710/
https://ncbi.nlm.nih.gov/pubmed/28642363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201612131
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