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Beyond the Trinity of ATM, ATR, and DNA-PK: Multiple Kinases Shape the DNA Damage Response in Concert With RNA Metabolism

Our genome is constantly exposed to endogenous and exogenous sources of DNA damage resulting in various alterations of the genetic code. DNA double-strand breaks (DSBs) are considered one of the most cytotoxic lesions. Several types of repair pathways act to repair DNA damage and maintain genome sta...

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Bibliografiske detaljer
Udgivet i:Front Mol Biosci
Main Authors: Burger, Kaspar, Ketley, Ruth F., Gullerova, Monika
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688092/
https://ncbi.nlm.nih.gov/pubmed/31428617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00061
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