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DNA Damage Sensing by the ATM and ATR Kinases

In eukaryotic cells, maintenance of genomic stability relies on the coordinated action of a network of cellular processes, including DNA replication, DNA repair, cell-cycle progression, and others. The DNA damage response (DDR) signaling pathway orchestrated by the ATM and ATR kinases is the central...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maréchal, Alexandre, Zou, Lee
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753707/
https://ncbi.nlm.nih.gov/pubmed/24003211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012716
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