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The THP1-SAC3-SUS1-CDC31 Complex Works in Transcription Elongation-mRNA Export Preventing RNA-mediated Genome Instability

The eukaryotic THO/TREX complex, involved in mRNP biogenesis, plays a key role in the maintenance of genome integrity in yeast. mRNA export factors such as Thp1-Sac3 also affect genome integrity, but their mutations have other phenotypes different from those of THO/TREX. Sus1 is a novel component of...

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Detalhes bibliográficos
Main Authors: González-Aguilera, Cristina, Tous, Cristina, Gómez-González, Belén, Huertas, Pablo, Luna, Rosa, Aguilera, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555943/
https://ncbi.nlm.nih.gov/pubmed/18667528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-04-0355
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