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The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability
The THO complex is a multimeric factor containing four polypeptides, Tho2, Hpr1, Mft1 and Thp2. Mutations in any of the genes encoding THO confer impairment of transcription and a transcription-dependent hyper-recombination phenotype, suggesting that THO has a functional role in gene expression. Usi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126085/ https://ncbi.nlm.nih.gov/pubmed/12093753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf335 |
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