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The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability

The THO complex is a multimeric factor containing four polypeptides, Tho2, Hpr1, Mft1 and Thp2. Mutations in any of the genes encoding THO confer impairment of transcription and a transcription-dependent hyper-recombination phenotype, suggesting that THO has a functional role in gene expression. Usi...

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Udgivet i:EMBO J
Principais autores: Jimeno, S., Rondón, A.G., Luna, R., Aguilera, A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
Fag:
Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126085/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093753/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf335
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