The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability
The THO complex is a multimeric factor containing four polypeptides, Tho2, Hpr1, Mft1 and Thp2. Mutations in any of the genes encoding THO confer impairment of transcription and a transcription-dependent hyper-recombination phenotype, suggesting that THO has a functional role in gene expression. Usi...
Guardat en:
| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126085/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093753/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf335 |
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