Sus1, Cdc31, and the Sac3 CID Region Form a Conserved Interaction Platform that Promotes Nuclear Pore Association and mRNA Export

The yeast Sac3:Cdc31:Sus1:Thp1 (TREX-2) complex facilitates the repositioning and association of actively transcribing genes with nuclear pores (NPCs)—“gene gating”—that is central to integrating transcription, processing, and mRNA nuclear export. We present here the crystal structure of Sus1 and Cd...

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Detalhes bibliográficos
Main Authors: Jani, Divyang, Lutz, Sheila, Marshall, Neil J., Fischer, Tamás, Köhler, Alwin, Ellisdon, Andrew M., Hurt, Ed, Stewart, Murray
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726291/
https://ncbi.nlm.nih.gov/pubmed/19328066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.01.033
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