Sus1, Cdc31, and the Sac3 CID Region Form a Conserved Interaction Platform that Promotes Nuclear Pore Association and mRNA Export

The yeast Sac3:Cdc31:Sus1:Thp1 (TREX-2) complex facilitates the repositioning and association of actively transcribing genes with nuclear pores (NPCs)—“gene gating”—that is central to integrating transcription, processing, and mRNA nuclear export. We present here the crystal structure of Sus1 and Cd...

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Main Authors: Jani, Divyang, Lutz, Sheila, Marshall, Neil J., Fischer, Tamás, Köhler, Alwin, Ellisdon, Andrew M., Hurt, Ed, Stewart, Murray
Format: Artigo
Language:Inglês
Published: Cell Press 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726291/
https://ncbi.nlm.nih.gov/pubmed/19328066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.01.033
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