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Bos taurus Ultralong CDR H3 Antibodies

Cow antibodies are unusual in having an exceptionally long third complementarity determining region of the heavy chain (CDR H3). These CDR H3s have a multitude of cysteines and form a distinct domain characterized by a β-ribbon “stalk” and disulfide bonded “knob”. Cows appear to utilize somatic hype...

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Détails bibliographiques
Publié dans:Curr Opin Struct Biol
Auteurs principaux: Vadnais, Melissa L., Smider, Vaughn V.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667352/
https://ncbi.nlm.nih.gov/pubmed/27295423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.05.004
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