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Purification and Biophysical Characterization of the Mre11-Rad50-Nbs1 Complex
The Mre11-Rad50-Nbs1 (MRN) complex coordinates the repair of DNA double-strand breaks, replication fork restart, meiosis, class-switch recombination, and telomere maintenance. As such, MRN is an essential molecular machine that has homologs in all organisms of life, from bacteriophage to humans. In...
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| Veröffentlicht in: | Methods Mol Biol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6667175/ https://ncbi.nlm.nih.gov/pubmed/31147924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9520-2_20 |
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