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Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

The Nijmegen breakage syndrome gene product (Nbs1) was shown recently to associate in vivo with the Mre11 and Rad50 proteins, which play pivotal roles in eukaryotic DNA double-strand break repair, meiotic recombination, and telomere maintenance. We show in this work that the triple complex of recomb...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Paull, Tanya T., Gellert, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316715/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10346816/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.10.1276
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