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Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

The Nijmegen breakage syndrome gene product (Nbs1) was shown recently to associate in vivo with the Mre11 and Rad50 proteins, which play pivotal roles in eukaryotic DNA double-strand break repair, meiotic recombination, and telomere maintenance. We show in this work that the triple complex of recomb...

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Hlavní autoři: Paull, Tanya T., Gellert, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC316715/
https://ncbi.nlm.nih.gov/pubmed/10346816
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