Nalaganje...
Cross-Seeding Fibrillation of Q/N-Rich Proteins Offers New Pathomechanism of Polyglutamine Diseases
A pathological hallmark of the Huntington's disease (HD) is intracellular inclusions containing a huntingtin (Htt) protein with an elongated polyglutamine tract. Aggregation of mutant Htt causes abnormal protein–protein interactions, and the functional dysregulation of aggregate-interacting pro...
Shranjeno v:
| izdano v: | J Neurosci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6665470/ https://ncbi.nlm.nih.gov/pubmed/19386911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0783-09.2009 |
| Oznake: |
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