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Post-aggregation Oxidation of Mutant Huntingtin Controls the Interactions between Aggregates

Aggregation of protein molecules is a pathological hallmark of many neurodegenerative diseases. Abnormal modifications have often been observed in the aggregated proteins, supporting the aggregation mechanism regulated by post-translational modifications on proteins. Modifications are in general ass...

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Detalhes bibliográficos
Main Authors: Mitomi, Yasushi, Nomura, Takao, Kurosawa, Masaru, Nukina, Nobuyuki, Furukawa, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464579/
https://ncbi.nlm.nih.gov/pubmed/22891249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.387035
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