Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders

Alpha-synuclein is a presynaptic protein that forms abnormal cytoplasmic aggregates in Lewy body disorders. Although nuclear alpha-synuclein localization has been described, its function in the nucleus is not well understood. We demonstrate that alpha-synuclein modulates DNA repair. First, alpha-syn...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Schaser, Allison J., Osterberg, Valerie R., Dent, Sydney E., Stackhouse, Teresa L., Wakeham, Colin M., Boutros, Sydney W., Weston, Leah J., Owen, Nichole, Weissman, Tamily A., Luna, Esteban, Raber, Jacob, Luk, Kelvin C., McCullough, Amanda K., Woltjer, Randall L., Unni, Vivek K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662836/
https://ncbi.nlm.nih.gov/pubmed/31358782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47227-z
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak