Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders

Alpha-synuclein is a presynaptic protein that forms abnormal cytoplasmic aggregates in Lewy body disorders. Although nuclear alpha-synuclein localization has been described, its function in the nucleus is not well understood. We demonstrate that alpha-synuclein modulates DNA repair. First, alpha-syn...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Schaser, Allison J., Osterberg, Valerie R., Dent, Sydney E., Stackhouse, Teresa L., Wakeham, Colin M., Boutros, Sydney W., Weston, Leah J., Owen, Nichole, Weissman, Tamily A., Luna, Esteban, Raber, Jacob, Luk, Kelvin C., McCullough, Amanda K., Woltjer, Randall L., Unni, Vivek K.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662836/
https://ncbi.nlm.nih.gov/pubmed/31358782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47227-z
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы