Pharmacodynamics of Tebipenem: New Options for Oral Treatment of Multidrug-Resistant Gram-Negative Infections

Tebipenem pivoxil HBr (TBPM-PI-HBr) is a novel orally bioavailable carbapenem. The active moiety is tebipenem. Tebipenem pivoxil is licensed for use in Japan in children with ear, nose, and throat infections and respiratory infections. The HBr salt was designed to improve drug substance and drug pro...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: McEntee, Laura, Johnson, Adam, Farrington, Nicola, Unsworth, Jennifer, Dane, Aaron, Jain, Akash, Cotroneo, Nicole, Critchley, Ian, Melnick, David, Parr, Thomas, Ambrose, Paul G., Das, Shampa, Hope, William
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2019
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658774/
https://ncbi.nlm.nih.gov/pubmed/31109982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00603-19
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