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Pharmacodynamics of Tebipenem: New Options for Oral Treatment of Multidrug-Resistant Gram-Negative Infections

Tebipenem pivoxil HBr (TBPM-PI-HBr) is a novel orally bioavailable carbapenem. The active moiety is tebipenem. Tebipenem pivoxil is licensed for use in Japan in children with ear, nose, and throat infections and respiratory infections. The HBr salt was designed to improve drug substance and drug pro...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: McEntee, Laura, Johnson, Adam, Farrington, Nicola, Unsworth, Jennifer, Dane, Aaron, Jain, Akash, Cotroneo, Nicole, Critchley, Ian, Melnick, David, Parr, Thomas, Ambrose, Paul G., Das, Shampa, Hope, William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658774/
https://ncbi.nlm.nih.gov/pubmed/31109982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00603-19
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