1304. Characterization of Tebipenem Pivoxil Hydrobromide Pharmacokinetics-Pharmacodynamics (PK-PD) in a Neutropenic Murine Acute Pyelonephritis (AP) Model

BACKGROUND: Tebipenem pivoxil hydrobromide (tebipenem HBr), an orally (PO) bioavailable prodrug of tebipenem, is a carbapenem with broad-spectrum activity against Gram-positive and -negative bacteria that is being developed for the treatment of patients with complicated urinary tract infections, inc...

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Bibliographic Details
Published in:Open Forum Infect Dis
Main Authors: VanScoy, Brian D, Fikes, Steven, Rubino, Christopher M, Bhavnani, Sujata M, Cotroneo, Nicole S, Critchley, Ian A, Parr, Thomas R, Ambrose, Paul G
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Poster Abstracts
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7776801/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofaa439.1487
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