Pharmacodynamics of the Orotomides against Aspergillus fumigatus: New Opportunities for Treatment of Multidrug-Resistant Fungal Disease

F901318 is an antifungal agent with a novel mechanism of action and potent activity against Aspergillus spp. An understanding of the pharmacodynamics (PD) of F901318 is required for selection of effective regimens for study in phase II and III clinical trials. Neutropenic murine and rabbit models of...

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Enregistré dans:
Détails bibliographiques
Publié dans:mBio
Auteurs principaux: Hope, William W., McEntee, Laura, Livermore, Joanne, Whalley, Sarah, Johnson, Adam, Farrington, Nicola, Kolamunnage-Dona, Ruwanthi, Schwartz, Julie, Kennedy, Anthony, Law, Derek, Birch, Michael, Rex, John H.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565967/
https://ncbi.nlm.nih.gov/pubmed/28830945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01157-17
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