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Pharmacodynamics of Isavuconazole in an Aspergillus fumigatus Mouse Infection Model

Azole resistance is an emerging problem in Aspergillus fumigatus which translates into treatment failure. Alternative treatments with new azoles may improve therapeutic outcome in invasive aspergillosis (IA) even for strains with decreased susceptibility to current azoles. The in vivo efficacy of 0....

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Publicat a:Antimicrob Agents Chemother
Autors principals: Seyedmousavi, Seyedmojtaba, Brüggemann, Roger J. M., Meis, Jacques F., Melchers, Willem J. G., Verweij, Paul E., Mouton, Johan W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394800/
https://ncbi.nlm.nih.gov/pubmed/25753636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04907-14
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