Pharmacodynamics of Anidulafungin against Clinical Aspergillus fumigatus Isolates in a Nonneutropenic Murine Model of Disseminated Aspergillosis

Azole resistance is an emerging increasing problem in Aspergillus fumigatus that results in treatment failure. Alternative treatments may improve the therapeutic outcome in patients with azole-resistant invasive aspergillosis (IA). Little is known about the in vivo efficacy of the echinocandin anidu...

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Autors principals: Seyedmousavi, Seyedmojtaba, Brüggemann, Roger J. M., Melchers, Willem J. G., Verweij, Paul E., Mouton, Johan W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535895/
https://ncbi.nlm.nih.gov/pubmed/23114773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01430-12
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