Pharmacodynamics of Cefepime Combined with the Novel Extended-Spectrum-β-Lactamase (ESBL) Inhibitor Enmetazobactam for Murine Pneumonia Caused by ESBL-Producing Klebsiella pneumoniae

Klebsiella pneumoniae strains that produce extended-spectrum beta lactamases (ESBLs) are a persistent public health threat. There are relatively few therapeutic options, and there is undue reliance on carbapenems. Alternative therapeutic options are urgently required. A combination of cefepime and t...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Johnson, Adam, McEntee, Laura, Farrington, Nicola, Kolamunnage-Dona, Ruwanthi, Franzoni, Samantha, Vezzelli, Alberto, Massimiliano, Mameli, Knechtle, Philipp, Belley, Adam, Dane, Aaron, Drusano, George, Das, Shampa, Hope, William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269479/
https://ncbi.nlm.nih.gov/pubmed/32253209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00180-20
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