Degree of MDM2 Amplification Affects Clinical Outcomes in Dedifferentiated Liposarcoma

BACKGROUND. Dedifferentiated liposarcomas (DDLPS) are mesenchymal tumors associated with universally poor response to treatment. Genomic amplification of murine double minute 2 (MDM2) is used as a diagnostic biomarker; however, no established biomarkers exist to guide DDLPS treatment. In the largest...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncologist
Egile Nagusiak: Bill, Kate Lynn J., Seligson, Nathan D., Hays, John L., Awasthi, Achal, Demoret, Bryce, Stets, Colin W., Duggan, Megan C., Bupathi, Manojkumar, Brock, Guy N., Millis, Sherri Z., Shakya, Reena, Timmers, Cynthia D., Wakely, Paul E., Pollock, Raphael E., Chen, James L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Inc. 2019
Gaiak:
Sarcomas
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656442/
https://ncbi.nlm.nih.gov/pubmed/31019022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2019-0047
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