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Cracking the riddle of dedifferentiated liposarcoma: is EV-MDM2 a key?

Dedifferentiated liposarcoma (DDLPS) is molecularly characterized by wt p53 and MDM2 gene amplification causing MDM2 protein over-production, the key oncogenic process in DDLPS. Commonly located in fat-bearing retroperitoneal areas, almost 60% of DDLPS patients undergo multifocal recurrence, typical...

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Bibliografiska uppgifter
I publikationen:Oncoscience
Huvudupphovsmän: Casadei, Lucia, Pollock, Raphael E
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105156/
https://ncbi.nlm.nih.gov/pubmed/32258243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.497
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