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MDM2 derived from dedifferentiated liposarcoma extracellular vesicles induces MMP2 production from preadipocytes

Dedifferentiated liposarcoma (DDLPS) is frequently diagnosed late and patients typically respond poorly to treatments. DDLPS is molecularly characterized by wild-type p53 and amplification of the MDM2 gene which results in overexpression of MDM2 protein, a key oncogenic process in DDLPS. In this stu...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Casadei, Lucia, Calore, Federica, Braggio, Danielle A., Zewdu, Abeba, Deshmukh, Ameya A., Fadda, Paolo, Lopez, Gonzalo, Wabitsch, Martin, Song, Chi, Leight, Jennifer L., Grignol, Valerie P., Lev, Dina, Croce, Carlo M., Pollock, Raphael E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774856/
https://ncbi.nlm.nih.gov/pubmed/31387924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0203
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