Discovery of SHR9352: A Highly Potent G Protein-Biased μ-Opioid Receptor Agonist

[Image: see text] Recently, targeting the G protein-biased signaling has emerged as an attractive therapeutic strategy for treating severe acute pain with the potential to reduce the side effect of the traditional opioid drug. Herein, we describe the discovery of a highly potent G protein-biased μ-o...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Li, Xin, He, Wei, Chen, Yang, Yang, Guimei, Wan, Hong, Zhang, Lei, Hu, Qiyue, Feng, Jun, Zhang, Zhigao, He, Feng, Bai, Chang, Zhang, Lianshan, You, Li, Tao, Weikang
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645658/
https://ncbi.nlm.nih.gov/pubmed/31457439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01452
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