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Discovery of SHR0687, a Highly Potent and Peripheral Nervous System-Restricted KOR Agonist
[Image: see text] Analgesics with no abuse liability are highly demanded in the market. KOR agonists have been proved to be strong analgesics without MOR agonist-related side effects, such as respiratory depression, tolerance, and dependence liability; however, activation of KOR in the central nervo...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | ACS Med Chem Lett |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Chemical
Society
2020
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| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7667827/ https://ncbi.nlm.nih.gov/pubmed/33214823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00287 |
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