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Determinants of Oligonucleotide Selectivity of APOBEC3B
APOBEC3B (A3B) is a prominent source of mutation in many cancers. To date, it has been difficult to capture the native protein-DNA interactions that confer A3B’s substrate specificity by crystallography due to the highly dynamic nature of wild-type A3B active site. We use computational tools to rest...
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| Veröffentlicht in: | J Chem Inf Model |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6644697/ https://ncbi.nlm.nih.gov/pubmed/30130104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.8b00427 |
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