APOBEC3B Nuclear Localization Requires Two Distinct N-Terminal Domain Surfaces

The APOBEC3 family of cytosine deaminases catalyzes the conversion of cytosines-to-uracils in single-stranded DNA. Traditionally, these enzymes are associated with antiviral immunity and restriction of DNA-based pathogens. However, a role for these enzymes in tumor evolution and metastatic disease h...

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Bibliographic Details
Published in:J Mol Biol
Main Authors: Salamango, Daniel J., McCann, Jennifer L., Demir, Özlem, Brown, William L., Amaro, Rommie E., Harris, Reuben S.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456046/
https://ncbi.nlm.nih.gov/pubmed/29787764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.04.044
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