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Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain
Functional and deep sequencing studies have combined to demonstrate the involvement of APOBEC3B in cancer mutagenesis. APOBEC3B is a single-stranded DNA cytosine deaminase that functions normally as a nuclear-localized restriction factor of DNA-based pathogens. However, it is overexpressed in cancer...
Tallennettuna:
| Julkaisussa: | J Biol Chem |
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| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653671/ https://ncbi.nlm.nih.gov/pubmed/26416889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.679951 |
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