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Intestinal FXR-mediated FGF15 production contributes to diurnal control of hepatic bile acid synthesis in mice

Hepatic bile acid synthesis is subject to complex modes of transcriptional control, in which the bile acid-activated nuclear receptor farnesoid X receptor (FXR) in liver and intestine-derived, FXR-controlled fibroblast growth factor 15 (Fgf15) are involved. The Fgf15 pathway is assumed to contribute...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Stroeve, Johanna HM, Brufau, Gemma, Stellaard, Frans, Gonzalez, Frank J, Staels, Bart, Kuipers, Folkert
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643294/
https://ncbi.nlm.nih.gov/pubmed/20531290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.107
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