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PROTECTIVE EFFECTS OF FXR ON HEPATIC LIPID ACCUMULATION ARE MEDIATED BY HEPATIC FXR AND INDEPENDENT OF INTESTINAL FGF15 SIGNAL
BACKGROUND AND AIMS: There is growing evidence that bile acids are involved in the regulation of triglyceride-, cholesterol-homeostasis and fat absorption. In this study organ-specific Fxr knockout mice were used to further investigate the influence of FXR in lipogenesis. METHODS: Liver- and intesti...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146754/ https://ncbi.nlm.nih.gov/pubmed/25156247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12456 |
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