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Bile Acids as Hormones: The FXR-FGF15/19 Pathway

While it has long been recognized that bile acids are essential for solubilizing lipophilic nutrients in the small intestine, the discovery in 1999 that bile acids serve as ligands for the nuclear receptor FXR opened the floodgates in terms of characterizing their actions as selective signaling mole...

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Detalhes bibliográficos
Publicado no:Dig Dis
Main Authors: Kliewer, Steven A., Mangelsdorf, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465534/
https://ncbi.nlm.nih.gov/pubmed/26045265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000371670
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