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Tissue-specific Actions of the Metabolic Hormones FGF15/19 and FGF21

Fibroblast growth factors (FGFs) 15/19 and 21 belong to a subfamily of FGFs that function as hormones. Produced in response to specific nutritional cues, they act on overlapping sets of cell surface receptors composed of classic FGF receptors in complex with βKlotho, and regulate metabolism and rela...

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Detalhes bibliográficos
Publicado no:Trends Endocrinol Metab
Main Authors: Owen, Bryn M., Mangelsdorf, David J., Kliewer, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277911/
https://ncbi.nlm.nih.gov/pubmed/25476453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2014.10.002
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