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Tissue-specific Actions of the Metabolic Hormones FGF15/19 and FGF21

Fibroblast growth factors (FGFs) 15/19 and 21 belong to a subfamily of FGFs that function as hormones. Produced in response to specific nutritional cues, they act on overlapping sets of cell surface receptors composed of classic FGF receptors in complex with βKlotho, and regulate metabolism and rela...

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Détails bibliographiques
Publié dans:Trends Endocrinol Metab
Auteurs principaux: Owen, Bryn M., Mangelsdorf, David J., Kliewer, Steven A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277911/
https://ncbi.nlm.nih.gov/pubmed/25476453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2014.10.002
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