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Tissue-specific Actions of the Metabolic Hormones FGF15/19 and FGF21

Fibroblast growth factors (FGFs) 15/19 and 21 belong to a subfamily of FGFs that function as hormones. Produced in response to specific nutritional cues, they act on overlapping sets of cell surface receptors composed of classic FGF receptors in complex with βKlotho, and regulate metabolism and rela...

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Bibliografiske detaljer
Udgivet i:Trends Endocrinol Metab
Main Authors: Owen, Bryn M., Mangelsdorf, David J., Kliewer, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277911/
https://ncbi.nlm.nih.gov/pubmed/25476453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2014.10.002
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