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Modulation of the intestinal bile acid–FXR–FGF15 axis improves alcoholic liver disease in mice

Alcoholic liver disease is associated with changes in the intestinal microbiota. Functional consequences of alcohol-associated dysbiosis are largely unknown. The aim of this study was to identify a mechanism of how changes in the intestinal microbiota contribute to alcoholic liver disease. Metagenom...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Hartmann, Phillipp, Hochrath, Katrin, Horvath, Angela, Chen, Peng, Seebauer, Caroline T., Llorente, Cristina, Wang, Lirui, Alnouti, Yazen, Fouts, Derrick E., Stärkel, Peter, Loomba, Rohit, Coulter, Sally, Liddle, Christopher, Yu, Ruth T., Ling, Lei, Rossi, Stephen J., DePaoli, Alex M., Downes, Michael, Evans, Ronald M., Brenner, David A., Schnabl, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962369/
https://ncbi.nlm.nih.gov/pubmed/29159825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29676
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