Modulation of the intestinal bile acid–FXR–FGF15 axis improves alcoholic liver disease in mice

Alcoholic liver disease is associated with changes in the intestinal microbiota. Functional consequences of alcohol-associated dysbiosis are largely unknown. The aim of this study was to identify a mechanism of how changes in the intestinal microbiota contribute to alcoholic liver disease. Metagenom...

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Détails bibliographiques
Publié dans:Hepatology
Auteurs principaux: Hartmann, Phillipp, Hochrath, Katrin, Horvath, Angela, Chen, Peng, Seebauer, Caroline T., Llorente, Cristina, Wang, Lirui, Alnouti, Yazen, Fouts, Derrick E., Stärkel, Peter, Loomba, Rohit, Coulter, Sally, Liddle, Christopher, Yu, Ruth T., Ling, Lei, Rossi, Stephen J., DePaoli, Alex M., Downes, Michael, Evans, Ronald M., Brenner, David A., Schnabl, Bernd
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962369/
https://ncbi.nlm.nih.gov/pubmed/29159825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29676
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