Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity

Nonalcoholic fatty liver disease (NAFLD) and obesity are characterized by altered gut microbiota, inflammation, and gut barrier dysfunction. Here, we investigated the role of mucin-2 (Muc2) as the major component of the intestinal mucus layer in the development of fatty liver disease and obesity. We...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Hartmann, Phillipp, Seebauer, Caroline T., Mazagova, Magdalena, Horvath, Angela, Wang, Lirui, Llorente, Cristina, Varki, Nissi M., Brandl, Katharina, Ho, Samuel B., Schnabl, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Inflammation, Immunity, and Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773827/
https://ncbi.nlm.nih.gov/pubmed/26702135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00094.2015
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