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Toll-Like Receptor 2-Mediated Intestinal Injury and Enteric Tumor Necrosis Factor Receptor I Contribute to Liver Fibrosis in Mice

BACKGROUND & AIMS: Progression of liver fibrosis in experimental models depends on gut-derived bacterial products, but little is known about mechanisms of disruption of the mucosal barrier or translocation. We used a mouse model of cholestatic liver disease to investigate mechanisms of intestina...

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Detalhes bibliográficos
Main Authors: Hartmann, Phillipp, Haimerl, Michael, Mazagova, Magdalena, Brenner, David A., Schnabl, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482543/
https://ncbi.nlm.nih.gov/pubmed/22841787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.07.099
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