Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity

Nonalcoholic fatty liver disease (NAFLD) and obesity are characterized by altered gut microbiota, inflammation, and gut barrier dysfunction. Here, we investigated the role of mucin-2 (Muc2) as the major component of the intestinal mucus layer in the development of fatty liver disease and obesity. We...

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Bibliografiset tiedot
Julkaisussa:Am J Physiol Gastrointest Liver Physiol
Päätekijät: Hartmann, Phillipp, Seebauer, Caroline T., Mazagova, Magdalena, Horvath, Angela, Wang, Lirui, Llorente, Cristina, Varki, Nissi M., Brandl, Katharina, Ho, Samuel B., Schnabl, Bernd
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2015
Aiheet:
Inflammation, Immunity, and Infection
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773827/
https://ncbi.nlm.nih.gov/pubmed/26702135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00094.2015
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