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Intestinal FXR-mediated FGF15 production contributes to diurnal control of hepatic bile acid synthesis in mice
Hepatic bile acid synthesis is subject to complex modes of transcriptional control, in which the bile acid-activated nuclear receptor farnesoid X receptor (FXR) in liver and intestine-derived, FXR-controlled fibroblast growth factor 15 (Fgf15) are involved. The Fgf15 pathway is assumed to contribute...
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| Pubblicato in: | Lab Invest |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6643294/ https://ncbi.nlm.nih.gov/pubmed/20531290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.107 |
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