Repression of intestinal transporters and FXR-FGF15 signaling explains bile acids dysregulation in experimental colitis-associated colon cancer

Bile acids (BAs) are important endogenous signaling molecules that play vital roles in the pathological development of various diseases including colitis-associated cancer (CAC). BAs were previously found dysregulated under conditions of CAC; however, the exact patterns and underlying molecular mech...

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Vydáno v:Oncotarget
Hlavní autoři: Cao, Lijuan, Che, Yuan, Meng, Tuo, Deng, Shanshan, Zhang, Jun, Zhao, Min, Xu, Wanfeng, Wang, Dandan, Pu, Zhichen, Wang, Guangji, Hao, Haiping
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609951/
https://ncbi.nlm.nih.gov/pubmed/28969019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18885
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