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Repair and translesion synthesis of O(6)-alkylguanine DNA lesions in human cells
O(6)-alkyl-2′-deoxyguanosine (O(6)-alkyl-dG) lesions are among the most mutagenic and prevalent alkylated DNA lesions that are associated with cancer initiation and progression. In this study, using a shuttle vector–based strand-specific PCR-competitive replication and adduct bypass assay in conjunc...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6643039/ https://ncbi.nlm.nih.gov/pubmed/31167778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009054 |
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