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Kinetic Analysis of Translesion Synthesis Opposite Bulky N(2)- and O(6)-Alkylguanine DNA Adducts by Human DNA Polymerase REV1
REV1, a Y family DNA polymerase (pol), is involved in replicative bypass past DNA lesions, so-called translesion DNA synthesis. In addition to a structural role as a scaffold protein, REV1 has been proposed to play a catalytic role as a dCTP transferase in translesion DNA synthesis past abasic and g...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527099/ https://ncbi.nlm.nih.gov/pubmed/18591245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801686200 |
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