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Selection and Characterization of a Nanobody Biosensor of GTP-Bound RHO Activities

RHO (Ras HOmologous) GTPases are molecular switches that activate, in their state bound to Guanosine triphosphate (GTP), key signaling pathways, which involve actin cytoskeleton dynamics. Previously, we selected the nanobody RH12, from a synthetic phage display library, which binds the GTP-bound act...

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Detalhes bibliográficos
Publicado no:Antibodies (Basel)
Main Authors: Keller, Laura, Bery, Nicolas, Tardy, Claudine, Ligat, Laetitia, Favre, Gilles, Rabbitts, Terence H., Olichon, Aurélien
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640709/
https://ncbi.nlm.nih.gov/pubmed/31544814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib8010008
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