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Selection and Characterization of a Nanobody Biosensor of GTP-Bound RHO Activities
RHO (Ras HOmologous) GTPases are molecular switches that activate, in their state bound to Guanosine triphosphate (GTP), key signaling pathways, which involve actin cytoskeleton dynamics. Previously, we selected the nanobody RH12, from a synthetic phage display library, which binds the GTP-bound act...
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| Publicado en: | Antibodies (Basel) |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6640709/ https://ncbi.nlm.nih.gov/pubmed/31544814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib8010008 |
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