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Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection

BACKGROUND: The Rho GTPases A, B and C proteins, members of the Rho family whose activity is regulated by GDP/GTP cycling, function in many cellular pathways controlling proliferation and have recently been implicated in tumorigenesis. Although overexpression of Rho GTPases has been correlated with...

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Detalhes bibliográficos
Main Authors: Goffinet, Marine, Chinestra, Patrick, Lajoie-Mazenc, Isabelle, Medale-Giamarchi, Claire, Favre, Gilles, Faye, Jean-Charles
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323369/
https://ncbi.nlm.nih.gov/pubmed/18377644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-8-34
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