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Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection
BACKGROUND: The Rho GTPases A, B and C proteins, members of the Rho family whose activity is regulated by GDP/GTP cycling, function in many cellular pathways controlling proliferation and have recently been implicated in tumorigenesis. Although overexpression of Rho GTPases has been correlated with...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323369/ https://ncbi.nlm.nih.gov/pubmed/18377644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-8-34 |
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