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NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies

In vitro selection of antibodies allows to obtain highly functional binders, rapidly and at lower cost. Here, we describe the first fully synthetic phage display library of humanized llama single domain antibody (NaLi-H1: Nanobody Library Humanized 1). Based on a humanized synthetic single domain an...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Moutel, Sandrine, Bery, Nicolas, Bernard, Virginie, Keller, Laura, Lemesre, Emilie, de Marco, Ario, Ligat, Laetitia, Rain, Jean-Christophe, Favre, Gilles, Olichon, Aurélien, Perez, Franck
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985285/
https://ncbi.nlm.nih.gov/pubmed/27434673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16228
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