NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies

In vitro selection of antibodies allows to obtain highly functional binders, rapidly and at lower cost. Here, we describe the first fully synthetic phage display library of humanized llama single domain antibody (NaLi-H1: Nanobody Library Humanized 1). Based on a humanized synthetic single domain an...

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Vydáno v:eLife
Hlavní autoři: Moutel, Sandrine, Bery, Nicolas, Bernard, Virginie, Keller, Laura, Lemesre, Emilie, de Marco, Ario, Ligat, Laetitia, Rain, Jean-Christophe, Favre, Gilles, Olichon, Aurélien, Perez, Franck
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2016
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985285/
https://ncbi.nlm.nih.gov/pubmed/27434673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16228
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