NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies

In vitro selection of antibodies allows to obtain highly functional binders, rapidly and at lower cost. Here, we describe the first fully synthetic phage display library of humanized llama single domain antibody (NaLi-H1: Nanobody Library Humanized 1). Based on a humanized synthetic single domain an...

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Detalles Bibliográficos
Publicado en:eLife
Autores principales: Moutel, Sandrine, Bery, Nicolas, Bernard, Virginie, Keller, Laura, Lemesre, Emilie, de Marco, Ario, Ligat, Laetitia, Rain, Jean-Christophe, Favre, Gilles, Olichon, Aurélien, Perez, Franck
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985285/
https://ncbi.nlm.nih.gov/pubmed/27434673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16228
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