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Structure of an inactive conformation of GTP-bound RhoA GTPase
By using (31)P NMR, we present evidence that the Rho family GTPase RhoA, like Ras GTPases, exists in an equilibrium of conformations when bound to GTP. High resolution crystal structures of RhoA bound to the GTP analog GMPPNP and to GDP show that they display a similar overall inactive conformation....
Gorde:
| Argitaratua izan da: | Structure |
|---|---|
| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8178163/ https://ncbi.nlm.nih.gov/pubmed/33497604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.12.015 |
| Etiketak: |
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